EXPERIMENTAL STUDY ON THE SHEAR PERFORMANCE OF STEEL-TRUSS-REINFORCED CONCRETE BEAM-COLUMN JOINTS


Improved Functionality of Exhausted Intrahepatic CXCR5+ CD8+ T Cells Contributes to Chronic Antigen Clearance Upon Immunomodulation

Chronic hepatotropic viral infections are characterized by exhausted CD8+ T cells in the presence of cognate antigen in the liver.The impairment of T cell response limits the control of chronic hepatotropic viruses.Immune-modulatory strategies are attractive options to re-invigorate exhausted T cells.However, in hepatotropic viral infections, the k

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Tomaso Casoni (1880-1933): A Pioneer Remembered

Tomaso Casoni (Figure 1A &1B) earned his fame by the test named after him [1].Casoni was first to describe a test for immediate allergic reaction to hydatid fluid injected into the skin (Figure 2).This was in a time when hydatid disease caused by infection by Echinococcus granlulosus was endemic in Europe, Africa and the Middle East in addition to

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